SubtiBank SubtiBank
Version comparison:

2017-8-11 16:0:32025-05-22 10:21:27

description

unknown

similar to ribosomal RNA large subunit methyltransferase I

locus

BSU38360

BSU_38360

geneLength

1188

1191

product

unknown

putative ribosomal RNA large subunit methyltransferase

ec

outlinks

bsu

BSU38360

BSU_38360

The protein

Catalyzed reaction/ biological activity

S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing C(5)-methylcytosine (according to Swiss-Prot)

The protein

Protein family

RlmI family (according to Swiss-Prot)

[SW|Methyltransferase superfamily] (according to UniProt)

Biological materials

Mutant

MGNA-B222 (ywbD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1221 NBRP B. subtilis, Japan]

MGNA-B222 (ywbD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1221 NBRP B. subtilis, Japan]

BKE38360 (Δ[[gene|ywbD]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE38360 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATATGTCGTCCTCTTTC, downstream forward: _UP4_TAAATGAAAAAGCTGCCCTG

BKK38360 (Δ[[gene|ywbD]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK38360 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATATGTCGTCCTCTTTC, downstream forward: _UP4_TAAATGAAAAAGCTGCCCTG

Biological materials

lacZ fusion

GP1614 ''amyE::p(ywbD-lacZ cat)'', constructed with pGP2150 based on [[protein|pAC5]], available in [SW| Jörg Stülke]'s lab

GP1614 ''amyE::p(ywbD-lacZ cat)'', constructed with pGP2150 based on [SW|pAC5], available in [SW| Jörg Stülke]'s lab

References

16430695

16430695, 18786544, 23016631

The protein

Paralogous protein(s)

[[this]]

The protein

[SW|Domains]

PUA domain (aa 1-79) (according to UniProt)

The protein

Structure

[PDB|3VSE] (from Staphylococcus aureus, 48% identity) [pubmed|23016631]